FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Orchestra BioMed, Inc.
 2. Date of Event Requiring Statement (Month/Day/Year)
05/31/2018		 3. Issuer Name and Ticker or Trading Symbol
Motus GI Holdings, Inc. [MOTS]
(Last)
(First)
(Middle)
150 UNION SQUARE DRIVE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW HOPE, PA 18938		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock, par value $0.0001 per share 2,000,000
D (1)
 

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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Orchestra BioMed, Inc.
150 UNION SQUARE DRIVE
NEW HOPE, PA 18938		     X    

Signatures

Orchestra BioMed, Inc., By: /s/ David P. Hochman, Chairman and Chief Executive Officer 06/11/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The common stock reported herein is owned directly by Orchestra BioMed, Inc., a Delaware corporation ("OBIO"). David P. Hochman, Darren R. Sherman and Geoffrey W. Smith are the directors of OBIO. Messrs. Hochman, Sherman and Smith jointly exercise dispositive and voting power over the shares owned by OBIO. Messrs. Hochman and Sherman are directors of Motus GI Holdings, Inc. and have separately reported their beneficial ownership of the common stock reported herein.

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