Quarterly report pursuant to Section 13 or 15(d)

Share-based compensation (Details Narrative)

v3.22.2
Share-based compensation (Details Narrative)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Feb. 10, 2022
shares
Jan. 05, 2022
USD ($)
$ / shares
shares
Jul. 16, 2021
USD ($)
$ / shares
shares
Jan. 27, 2021
USD ($)
$ / shares
shares
Jan. 20, 2021
USD ($)
$ / shares
shares
Aug. 28, 2020
$ / shares
shares
Dec. 31, 2016
Jun. 30, 2022
USD ($)
$ / shares
shares
Mar. 31, 2022
USD ($)
shares
Jun. 30, 2021
USD ($)
shares
Mar. 31, 2021
USD ($)
shares
Jun. 30, 2022
USD ($)
$ / shares
shares
Jun. 30, 2021
USD ($)
shares
Dec. 31, 2021
$ / shares
shares
Jan. 02, 2022
shares
Jan. 22, 2021
shares
Feb. 29, 2020
$ / shares
shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Share based compensation options, grants | shares                       98,747          
Share based compnesation plan modification, incremental cost                       $ 26          
General and administrative expense               $ 2,075   $ 2,345   $ 4,189 $ 4,789        
Common stock par value | $ / shares               $ 0.0001       $ 0.0001   $ 0.0001      
Proceeds from warrant exercises       $ 11,000               11,959        
Number of warrants were exercisable | shares                       394,577          
Share based compensation arrangement by share based payment award non options outstanding | $ / shares               50.87       $ 50.87          
Grant date fair value | $ / shares               $ 5.0       $ 8.80          
Stock based compensation for stock options               $ 461   1,010   $ 982 1,929        
Stock option weighted average                       7 years 6 months 29 days          
Unamortization stock compensation                          
Restricted Stock Units (RSUs) [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Vested and unissued restricted stock units | shares                           3,140      
Unamortization stock compensation                       $ 575          
Share based payment award equity instruments other than options outstanding weighted average remaining contractual terms                       10 months 13 days          
Equity Option [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Stock based compensation for stock options                       $ 1,524          
Stock option weighted average                       1 year 3 days          
Number of outstanding options to purchase of common stock | shares               271,808       271,808          
Weighted-average exercise price per share | $ / shares               $ 56.16       $ 56.16          
Share-based compensation of stock option               $ 302   $ 680   $ 586 1,349        
2016 Equity Incentive Plan [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Common stock, capital shares reserved for future issuance | shares                             86,433    
Number of common stock authorized for issuance | shares                             524,783    
Common stock available for future grant, shares | shares               13,401       13,401          
Warrant [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Fair value adjustment of warrants         $ 355                        
Share based compensation arrangement by share based payment award non options outstanding | $ / shares               $ 50.87       $ 50.87   $ 54.76      
Warrant [Member] | Measurement Input, Risk Free Interest Rate [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input         0.19                        
Warrant [Member] | Measurement Input, Expected Term [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants term         3 years                        
Warrant [Member] | Measurement Input, Price Volatility [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input         100.99                        
Warrant [Member] | Measurement Input, Expected Dividend Rate [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input         0                        
Private Placement Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Fair value of warrants outstanding | shares       400,000                          
Warrant exercise | shares                               36,681  
Warrant exercisable remaining | shares       400,000                          
Cash fees                         300        
New Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares       $ 42.40                          
Warrants term       5 years                          
Warrant exercisable remaining | shares       300,000                          
Share price | $ / shares       $ 0.75                          
Cash paid payment per share | $ / shares       $ 2                          
Warrants were issued       $ 600,000                          
Deemed dividend                         6,145        
Cash fees                         200        
New Warrants [Member] | Four Tranches [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Fair value adjustment of warrants                         $ 6,745        
Fair value of warrants outstanding | shares                   300,000     300,000        
New Warrants [Member] | Measurement Input, Risk Free Interest Rate [Member] | Maximum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input       0.57                          
New Warrants [Member] | Measurement Input, Risk Free Interest Rate [Member] | Minimum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input       0.41                          
New Warrants [Member] | Measurement Input, Expected Term [Member] | Maximum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants term       5 years                          
New Warrants [Member] | Measurement Input, Expected Term [Member] | Minimum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants term       4 years 11 months 12 days                          
New Warrants [Member] | Measurement Input, Price Volatility [Member] | Maximum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input       103.23                          
New Warrants [Member] | Measurement Input, Price Volatility [Member] | Minimum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input       103.00                          
New Warrants [Member] | Measurement Input, Expected Dividend Rate [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input       0                          
Common Stock [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Number of shares issued during the period | shares               4,174 13,721 2,654 3,295            
Unamortization stock compensation                          
Common Stock [Member] | 2016 Equity Incentive Plan [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Stock option annually percentage             6.00%                    
Services Agreement [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares                                 $ 10
General and administrative expense               0   $ 89   $ 30 $ 148        
Services Agreement [Member] | Warrant [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares         $ 35                        
Warrants to purchase common stock | shares         17,001                        
Vesting description         vest over a one-year period on a monthly basis                        
Warrants term         3 years                        
Services Agreement [Member] | Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants to purchase of common stock | shares                                 6,000
Warrants exercise price | $ / shares                                 $ 56.60
Services Agreement [Member] | Replacement Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants to purchase of common stock | shares                                 6,000
Securities Purchase Agreement [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Number of stock sold, shares | shares           160,000                      
Common stock par value | $ / shares           $ 0.0001                      
Securities Purchase Agreement [Member] | PreFunded Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares           $ 0.02                      
Warrants to purchase common stock | shares           276,681       276,681     276,681        
Proceeds from repurchase of equity                       6          
Securities Purchase Agreement [Member] | Private Placement Warrants [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares           $ 26                      
Securities Purchase Agreement [Member] | Private Placement Warrants [Member] | Maximum [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants to purchase common stock | shares           436,681                      
Kreos Loan Agreement [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares     $ 20.948                            
Warrants to purchase common stock | shares     9,547                            
Fair value adjustment of warrants                       165          
Kreos Loan Agreement [Member] | Warrant [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants exercise price | $ / shares     $ 20.95                            
Warrants to purchase common stock | shares     9,547                            
Warrants term     10 years                            
Fair value adjustment of warrants     $ 168                            
Proceeds from loan received     $ 165                            
Kreos Loan Agreement [Member] | Warrant [Member] | Measurement Input, Risk Free Interest Rate [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input     1.31                            
Kreos Loan Agreement [Member] | Warrant [Member] | Measurement Input, Price Volatility [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input     108.87                            
Kreos Loan Agreement [Member] | Warrant [Member] | Measurement Input, Discount Rate [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Warrants and rights outstanding, measurement input     0                            
NonEmployee [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Share based compensation options, grants | shares   24,458                              
Fair value of common stock | $ / shares   $ 9.60                              
Cash compensation   $ 235                              
Director [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Officers compensation               61       118          
Prepaid expense               117       117          
Executive Officer [Member] | Restricted Stock Units (RSUs) [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Vesting description which vest over a three-year period on a quarterly basis                                
Number of shares issued during the period | shares 18,250                                
Ceo, Executives and Directors [Member] | Restricted Stock Units (RSUs) [Member]                                  
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                                  
Other general and administrative expense               $ 159       $ 340